Alternative Oxidase Expression in the Mouse Enables Bypassing Cytochrome c Oxidase Blockade and Limits Mitochondrial ROS Overproduction

Cyanide-resistant non-phosphorylating respiration is known in mitochondria from plants, fungi, and microorganisms but is absent in mammals. It results from the activity of an alternative oxidase (AOX) that conveys electrons directly from the respiratory chain (RC) ubiquinol pool to oxygen. AOX thus...

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Dettagli Bibliografici
Autori principali: El-Khoury, Riyad, Dufour, Eric, Rak, Malgorzata, Ramanantsoa, Nelina, Grandchamp, Nicolas, Csaba, Zsolt, Duvillié, Bertrand, Bénit, Paule, Gallego, Jorge, Gressens, Pierre, Sarkis, Chamsy, Jacobs, Howard T., Rustin, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536694/
https://ncbi.nlm.nih.gov/pubmed/23300486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003182
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