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WNK1/HSN2 Mutation in Human Peripheral Neuropathy Deregulates KCC2 Expression and Posterior Lateral Line Development in Zebrafish (Danio rerio)

Hereditary sensory and autonomic neuropathy type 2 (HSNAII) is a rare pathology characterized by an early onset of severe sensory loss (all modalities) in the distal limbs. It is due to autosomal recessive mutations confined to exon “HSN2” of the WNK1 (with-no-lysine protein kinase 1) serine-threoni...

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Bibliografski detalji
Glavni autori: Bercier, Valérie, Brustein, Edna, Liao, Meijiang, Dion, Patrick A., Lafrenière, Ronald G., Rouleau, Guy A., Drapeau, Pierre
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536653/
https://ncbi.nlm.nih.gov/pubmed/23300475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003124
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