Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease

BACKGROUND: Juvenile Idiopathic Arthritis (JIA) is a complex autoimmune rheumatic disease of largely unknown cause. Evidence is growing that epigenetic variation, particularly DNA methylation, is associated with autoimmune disease. However, nothing is currently known about the potential role of aber...

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Main Authors: Ellis, Justine A, Munro, Jane E, Chavez, Raul A, Gordon, Lavinia, Joo, Jihoon E, Akikusa, Jonathan D, Allen, Roger C, Ponsonby, Anne-Louise, Craig, Jeffrey M, Saffery, Richard
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536591/
https://ncbi.nlm.nih.gov/pubmed/23148518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-4-20
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