Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease

BACKGROUND: Juvenile Idiopathic Arthritis (JIA) is a complex autoimmune rheumatic disease of largely unknown cause. Evidence is growing that epigenetic variation, particularly DNA methylation, is associated with autoimmune disease. However, nothing is currently known about the potential role of aber...

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Detalhes bibliográficos
Main Authors: Ellis, Justine A, Munro, Jane E, Chavez, Raul A, Gordon, Lavinia, Joo, Jihoon E, Akikusa, Jonathan D, Allen, Roger C, Ponsonby, Anne-Louise, Craig, Jeffrey M, Saffery, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536591/
https://ncbi.nlm.nih.gov/pubmed/23148518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-4-20
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