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Deterministic global optimization algorithm based on outer approximation for the parameter estimation of nonlinear dynamic biological systems
BACKGROUND: The estimation of parameter values for mathematical models of biological systems is an optimization problem that is particularly challenging due to the nonlinearities involved. One major difficulty is the existence of multiple minima in which standard optimization methods may fall during...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536584/ https://ncbi.nlm.nih.gov/pubmed/22574924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-90 |
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