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Role of Interferon Regulatory Factor 3-Mediated Apoptosis in the Establishment and Maintenance of Persistent Infection by Sendai Virus

Infection of cultured cells by paramyxoviruses causes cell death, mediated by a newly discovered apoptotic pathway activated by virus infection. The key proapoptotic protein in this pathway is interferon regulatory factor 3 (IRF-3), which upon activation by virus infection binds BAX, translocates it...

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Autors principals: Chattopadhyay, Saurabh, Fensterl, Volker, Zhang, Ying, Veleeparambil, Manoj, Yamashita, Michifumi, Sen, Ganes C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536409/
https://ncbi.nlm.nih.gov/pubmed/23077293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01853-12
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