Phosphatidylinositol 3-Kinase Signaling Delays Sendai Virus-Induced Apoptosis by Preventing XIAP Degradation

Sendai virus (SeV) infection causes apoptosis, which is manifested only late after infection; however, inhibition of phosphatidylinositol 3-kinase (PI3K) dramatically accelerates the process. We report here that rapid apoptosis uses the same mitochondrial apoptotic pathway as slow apoptosis. Cytopla...

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Main Authors: White, Christine L., Chattopadhyay, Saurabh, Sen, Ganes C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Cellular Response to Infection
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126159/
https://ncbi.nlm.nih.gov/pubmed/21367892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00053-11
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