Mechanistic Study of Broadly Neutralizing Human Monoclonal Antibodies against Dengue Virus That Target the Fusion Loop

There are no available vaccines for dengue, the most important mosquito-transmitted viral disease. Mechanistic studies with anti-dengue virus (DENV) human monoclonal antibodies (hMAbs) provide a rational approach to identify and characterize neutralizing epitopes on DENV structural proteins that can...

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Hlavní autoři: Costin, Joshua M., Zaitseva, Elena, Kahle, Kristen M., Nicholson, Cindo O., Rowe, Dawne K., Graham, Amanda S., Bazzone, Lindsey E., Hogancamp, Greg, Figueroa Sierra, Marielys, Fong, Rachel H., Yang, Sung-Tae, Lin, Li, Robinson, James E., Doranz, Benjamin J., Chernomordik, Leonid V., Michael, Scott F., Schieffelin, John S., Isern, Sharon
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536401/
https://ncbi.nlm.nih.gov/pubmed/23077306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02273-12
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