Release of Dengue Virus Genome Induced by a Peptide Inhibitor

Dengue virus infects approximately 100 million people annually, but there is no available therapeutic treatment. The mimetic peptide, DN59, consists of residues corresponding to the membrane interacting, amphipathic stem region of the dengue virus envelope (E) glycoprotein. This peptide is inhibitor...

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Detalhes bibliográficos
Main Authors: Lok, Shee-Mei, Costin, Joshua M., Hrobowski, Yancey M., Hoffmann, Andrew R., Rowe, Dawne K., Kukkaro, Petra, Holdaway, Heather, Chipman, Paul, Fontaine, Krystal A., Holbrook, Michael R., Garry, Robert F., Kostyuchenko, Victor, Wimley, William C., Isern, Sharon, Rossmann, Michael G., Michael, Scott F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511436/
https://ncbi.nlm.nih.gov/pubmed/23226444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050995
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