Release of Dengue Virus Genome Induced by a Peptide Inhibitor

Dengue virus infects approximately 100 million people annually, but there is no available therapeutic treatment. The mimetic peptide, DN59, consists of residues corresponding to the membrane interacting, amphipathic stem region of the dengue virus envelope (E) glycoprotein. This peptide is inhibitor...

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Autori principali: Lok, Shee-Mei, Costin, Joshua M., Hrobowski, Yancey M., Hoffmann, Andrew R., Rowe, Dawne K., Kukkaro, Petra, Holdaway, Heather, Chipman, Paul, Fontaine, Krystal A., Holbrook, Michael R., Garry, Robert F., Kostyuchenko, Victor, Wimley, William C., Isern, Sharon, Rossmann, Michael G., Michael, Scott F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511436/
https://ncbi.nlm.nih.gov/pubmed/23226444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050995
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