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APOBEC3G Restricts HIV-1 to a Greater Extent than APOBEC3F and APOBEC3DE in Human Primary CD4(+) T Cells and Macrophages

APOBEC3 proteins inhibit HIV-1 replication in experimental systems and induce hypermutation in infected patients; however, the relative contributions of several APOBEC3 proteins to restriction of HIV-1 replication in the absence of the viral Vif protein in human primary CD4(+) T cells and macrophage...

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Detalhes bibliográficos
Main Authors: Chaipan, Chawaree, Smith, Jessica L., Hu, Wei-Shau, Pathak, Vinay K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536366/
https://ncbi.nlm.nih.gov/pubmed/23097438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00676-12
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