Hsp70 Is a Novel Posttranscriptional Regulator of Gene Expression That Binds and Stabilizes Selected mRNAs Containing AU-Rich Elements

The AU-rich elements (AREs) encoded within many mRNA 3′ untranslated regions (3′UTRs) are targets for factors that control transcript longevity and translational efficiency. Hsp70, best known as a protein chaperone with well-defined peptide-refolding properties, is known to interact with ARE-like RN...

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Hauptverfasser: Kishor, Aparna, Tandukar, Bishal, Ly, Yann V., Toth, Eric A., Suarez, Yvelisse, Brewer, Gary, Wilson, Gerald M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536313/
https://ncbi.nlm.nih.gov/pubmed/23109422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01275-12
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