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Molecular Mechanisms of N-Formyl-Methionyl-Leucyl-Phenylalanine-Induced Superoxide Generation and Degranulation in Mouse Neutrophils: Phospholipase D Is Dispensable

Phospholipase D (PLD), which produces the lipid messenger phosphatidic acid (PA), has been implicated in superoxide generation and degranulation in neutrophils. The basis for this conclusion is the observation that primary alcohols, which interfere with PLD-catalyzed PA production, inhibit these neu...

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Hlavní autoři: Sato, Takanobu, Hongu, Tsunaki, Sakamoto, Megumi, Funakoshi, Yuji, Kanaho, Yasunori
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536298/
https://ncbi.nlm.nih.gov/pubmed/23109426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00869-12
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