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Cryptococcus neoformans Requires the ESCRT Protein Vps23 for Iron Acquisition from Heme, for Capsule Formation, and for Virulence
Iron availability is a key regulator of virulence factor elaboration in Cryptococcus neoformans, the causative agent of fungal meningoencephalitis in HIV/AIDS patients. In addition, iron is an essential nutrient for pathogen proliferation in mammalian hosts but little is known about the mechanisms o...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Microbiology
2013
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536123/ https://ncbi.nlm.nih.gov/pubmed/23132495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01037-12 |
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