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Cryptococcus neoformans Requires the ESCRT Protein Vps23 for Iron Acquisition from Heme, for Capsule Formation, and for Virulence

Iron availability is a key regulator of virulence factor elaboration in Cryptococcus neoformans, the causative agent of fungal meningoencephalitis in HIV/AIDS patients. In addition, iron is an essential nutrient for pathogen proliferation in mammalian hosts but little is known about the mechanisms o...

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Autori principali: Hu, Guanggan, Caza, Mélissa, Cadieux, Brigitte, Chan, Vivienne, Liu, Victor, Kronstad, James
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536123/
https://ncbi.nlm.nih.gov/pubmed/23132495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01037-12
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