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Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity

BACKGROUND: The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth arrest and apoptosis. p53 activation is regulated by post-translational modification, including phosphorylation of the N-terminal transact...

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Detaylı Bibliyografya
Asıl Yazarlar: Turenne, Gaetan A, Price, Brendan D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC35361/
https://ncbi.nlm.nih.gov/pubmed/11483158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-2-12
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