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Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity

BACKGROUND: The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth arrest and apoptosis. p53 activation is regulated by post-translational modification, including phosphorylation of the N-terminal transact...

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Udgivet i:BMC Cell Biol
Principais autores: Turenne, Gaetan A, Price, Brendan D
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2001
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC35361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-2-12
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