Lyn but not Fyn kinase controls IgG-Mediated Systemic Anaphylaxis

Anaphylaxis is a rapid, life-threatening hypersensitivity reaction. Until recently, it was mainly attributed to histamine released by mast cells activated by allergen crosslinking (XL) of FcεRI-bound allergen-specific IgE. However, recent reports established that anaphylaxis could also be triggered...

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Hauptverfasser: Falanga, Yves T., Chaimowitz, Natalia S., Charles, Nicolas, Finkelman, Fred D., Pullen, Nicholas A., Barbour, Suzanne, Dholaria, Kevin, Faber, Travis, Kolawole, Motunrayo, Huang, Bernice, Odom, Sandra, Rivera, Juan, Carlyon, Jason, Conrad, Daniel H., Spiegel, Sarah, Oskeritzian, Carole A., Ryan, John J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536057/
https://ncbi.nlm.nih.gov/pubmed/22450804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003223
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