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Fyn Kinase Is Required for Optimal Humoral Responses
The generation of antigen-specific antibodies and the development of immunological memory require collaboration between B and T cells. T cell-secreted IL-4 is important for B cell survival, isotype switch to IgG1 and IgE, affinity maturation, and the development of germinal centers (GC). Fyn, a memb...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620480/ https://ncbi.nlm.nih.gov/pubmed/23593269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060640 |
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