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A Mutation of the RNA Polymerase β′ Subunit (rpoC) Confers Cephalosporin Resistance in Bacillus subtilis

In bacteria, mutations affecting the major catalytic subunits of RNA polymerase (encoded by rpoB and rpoC) emerge in response to a variety of selective pressures. Here we isolated a Bacillus subtilis strain with high-level resistance to cefuroxime (CEF). Whole-genome resequencing revealed only one m...

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Hlavní autoři: Lee, Yong Heon, Nam, Ki Hyun, Helmann, John D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535988/
https://ncbi.nlm.nih.gov/pubmed/23070162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01449-12
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