Posaconazole Pharmacodynamic Target Determination against Wild-Type and Cyp51 Mutant Isolates of Aspergillus fumigatus in an In Vivo Model of Invasive Pulmonary Aspergillosis

Invasive pulmonary aspergillosis (IPA) is a devastating disease of immunocompromised patients. Pharmacodynamic (PD) examination of antifungal drug therapy in IPA is one strategy that may improve outcomes. The current study explored the PD target of posaconazole in an immunocompromised murine model o...

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Detaylı Bibliyografya
Asıl Yazarlar: Lepak, Alexander J., Marchillo, Karen, VanHecker, Jaimie, Andes, David R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Experimental Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535976/
https://ncbi.nlm.nih.gov/pubmed/23147740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01279-12
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