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Alginate Lyase Exhibits Catalysis-Independent Biofilm Dispersion and Antibiotic Synergy

More than 2 decades of study support the hypothesis that alginate lyases are promising therapeutic candidates for treating mucoid Pseudomonas aeruginosa infections. In particular, the enzymes' ability to degrade alginate, a key component of mucoid biofilm matrix, has been the presumed mechanism...

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Autors principals: Lamppa, John W., Griswold, Karl E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535929/
https://ncbi.nlm.nih.gov/pubmed/23070175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01789-12
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