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Alginate Lyase Exhibits Catalysis-Independent Biofilm Dispersion and Antibiotic Synergy
More than 2 decades of study support the hypothesis that alginate lyases are promising therapeutic candidates for treating mucoid Pseudomonas aeruginosa infections. In particular, the enzymes' ability to degrade alginate, a key component of mucoid biofilm matrix, has been the presumed mechanism...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535929/ https://ncbi.nlm.nih.gov/pubmed/23070175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01789-12 |
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