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Intracellular Trafficking and Glycobiology of TbPDI2, a Stage-Specific Protein Disulfide Isomerase in Trypanosoma brucei

Trypanosoma brucei protein disulfide isomerase 2 (TbPDI2) is a bloodstream stage-specific lumenal endoplasmic reticulum (ER) glycoprotein. ER localization is dependent on the TbPDI2 C-terminal tetrapeptide (KQDL) and is mediated by TbERD2, an orthologue of the yeast ER retrieval receptor. Consistent...

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Bibliographic Details
Main Authors: Schwartz, Kevin J., Peck, Ronald F., Bangs, James D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535847/
https://ncbi.nlm.nih.gov/pubmed/23159520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00293-12
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