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Synthetic spatially graded Rac activation drives cell polarization and movement
Migrating cells possess intracellular gradients of active Rho GTPases, which serve as central hubs in transducing signals from extracellular receptors to cytoskeletal and adhesive machinery. However, it is unknown whether shallow exogenously induced intracellular gradients of Rho GTPases are suffici...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535611/ https://ncbi.nlm.nih.gov/pubmed/23185021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210295109 |
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