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Synthetic spatially graded Rac activation drives cell polarization and movement
Migrating cells possess intracellular gradients of active Rho GTPases, which serve as central hubs in transducing signals from extracellular receptors to cytoskeletal and adhesive machinery. However, it is unknown whether shallow exogenously induced intracellular gradients of Rho GTPases are suffici...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535611/ https://ncbi.nlm.nih.gov/pubmed/23185021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210295109 |
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