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Structural elements in the Girk1 subunit that potentiate G protein–gated potassium channel activity

G protein–gated inwardly rectifying K(+) (Girk/K(IR)3) channels mediate the inhibitory effect of many neurotransmitters on excitable cells. Girk channels are tetramers consisting of various combinations of four mammalian Girk subunits (Girk1 to -4). Although Girk1 is unable to form functional homome...

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Autors principals: Wydeven, Nicole, Young, Daniele, Mirkovic, Kelsey, Wickman, Kevin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535602/
https://ncbi.nlm.nih.gov/pubmed/23236146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212019110
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