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A novel human autoantigen, endothelial cell growth factor, is a target of T and B cell responses in patients with Lyme disease

OBJECTIVE: Autoantigen presentation by HLA-DR molecules is thought to be a central component of many autoimmune diseases, but uncovering disease-relevant autoantigens has been a difficult challenge. Our goal was to identify autoantigens in patients with antibiotic-refractory Lyme arthritis, which is...

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Main Authors: Drouin, Elise E., Seward, Robert J., Strle, Klemen, McHugh, Gail, Katchar, Kianoosh, Londoño, Diana, Yao, Chunxiang, Costello, Catherine E., Steere, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535550/
https://ncbi.nlm.nih.gov/pubmed/23044924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37732
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