Tuning of Alternative Splicing - Switch From Proto-Oncogene to Tumor Suppressor

STAT5B, a specific member of the STAT family, is intimately associated with prostate tumor progression. While the full form of STAT5B is thought to promote tumor progression, a naturally occurring truncated isoform acts as a tumor suppressor. We previously demonstrated that truncated STAT5 is genera...

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Bibliographic Details
Main Authors: Shchelkunova, Aleksandra, Ermolinsky, Boris, Boyle, Meghan, Mendez, Ivan, Lehker, Michael, Martirosyan, Karen S., Kazansky, Alexander V.
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2012
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535533/
https://ncbi.nlm.nih.gov/pubmed/23289016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.5194
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