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Isotopically nonstationary (13)C flux analysis of Myc-induced metabolic reprogramming in B-cells
We assessed several methods of (13)C metabolic flux analysis (MFA) and found that isotopically nonstationary MFA achieved maximum flux resolution in cultured P493-6 B-cells, which have been engineered to provide tunable expression of the Myc oncoprotein. Comparison of metabolic flux maps obtained un...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535509/ https://ncbi.nlm.nih.gov/pubmed/22898717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2012.07.008 |
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