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Isotopically nonstationary (13)C flux analysis of Myc-induced metabolic reprogramming in B-cells

We assessed several methods of (13)C metabolic flux analysis (MFA) and found that isotopically nonstationary MFA achieved maximum flux resolution in cultured P493-6 B-cells, which have been engineered to provide tunable expression of the Myc oncoprotein. Comparison of metabolic flux maps obtained un...

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Hlavní autoři: Murphy, Taylor A., Dang, Chi V., Young, Jamey D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535509/
https://ncbi.nlm.nih.gov/pubmed/22898717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2012.07.008
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