Mutant of herpes simplex virus type 2 with temperature-sensitive lesions affecting virion thermostability and DNase activity: identification of the lethal mutation and physical mapping of the nuc-lesion.

We had previously shown that a temperature-sensitive (ts) mutant of herpes simplex virus type 2 strain HG52, ts13, induced a heat-labile DNase activity in infected cells (B. Francke, H. Moss, M. C. Timbury, and J. Hay, J. Virol. 26:209-213, 1978). Earlier work indicated that the mutant also possesse...

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Detalles Bibliográficos
Main Authors: Chartrand, P, Timbury, M C, Hay, J, Moss, H
Formato: Artigo
Idioma:Inglês
Publicado: 1979
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC353536/
https://ncbi.nlm.nih.gov/pubmed/232166
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