Mutant of herpes simplex virus type 2 with temperature-sensitive lesions affecting virion thermostability and DNase activity: identification of the lethal mutation and physical mapping of the nuc-lesion.

We had previously shown that a temperature-sensitive (ts) mutant of herpes simplex virus type 2 strain HG52, ts13, induced a heat-labile DNase activity in infected cells (B. Francke, H. Moss, M. C. Timbury, and J. Hay, J. Virol. 26:209-213, 1978). Earlier work indicated that the mutant also possesse...

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出版年:	J Virol
主要な著者:	Chartrand, P, Timbury, M C, Hay, J, Moss, H
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1979
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/232166/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.32.1.140-146.1979
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Mutant of herpes simplex virus type 2 with temperature-sensitive lesions affecting virion thermostability and DNase activity: identification of the lethal mutation and physical mapping of the nuc-lesion.

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