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Wingless Signaling at Synapses Is Through Cleavage and Nuclear Import of Receptor DFrizzled2

Wingless secretion provides pivotal signals during development by activating transcription of target genes. At Drosophila synapses, Wingless is secreted from presynaptic terminals and is required for synaptic growth and differentiation. Wingless binds the seven-pass transmembrane DFrizzled2 receptor...

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Hlavní autoři: Mathew, Dennis, Ataman, Bulent, Chen, Jinyun, Zhang, Yali, Cumberledge, Susan, Budnik, Vivian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535279/
https://ncbi.nlm.nih.gov/pubmed/16311339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1117051
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