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Nucleus to Synapse Nesprin1 Railroad Tracks Direct Synapse Maturation Through RNA Localization
An important mechanism underlying synapse development and plasticity is the localization of mRNAs that travel from the nucleus to synaptic sites. Here we demonstrate that the giant nuclear-associated Nesprin1 (dNesp1) forms striated F-actin-based filaments, that we dubbed “railroad tracks”, that spa...
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| izdano v: | Neuron |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4657559/ https://ncbi.nlm.nih.gov/pubmed/25959729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.04.006 |
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