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Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis

Post-translational modifications (PTMs) of histones are an essential feature in the dynamic regulation of chromatin. One of these modifications, ubiquitylation, has been speculated to directly influence the stability of the nucleosome, which represents the basic building block of chromatin. Here we...

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Autori principali: Fierz, Beat, Kilic, Sinan, Hieb, Aaron R., Luger, Karolin, Muir, Tom W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535264/
https://ncbi.nlm.nih.gov/pubmed/23163596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja308908p
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