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Determination of the Dominant Arachidonic Acid Cytochrome P450 Monooxygenases in Rat Heart, Lung, Kidney, and Liver: Protein Expression and Metabolite Kinetics

Cytochrome P450 (P450)-derived arachidonic acid (AA) metabolites serve pivotal physiological roles. Therefore, it is important to determine the dominant P450 AA monooxygenases in different organs. We investigated the P450 AA monooxygenases protein expression as well as regioselectivity, immunoinhibi...

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Bibliographische Detailangaben
Hauptverfasser: El-Sherbeni, Ahmed A., Aboutabl, Mona E., Zordoky, Beshay N. M., Anwar-Mohamed, Anwar, El-Kadi, Ayman O. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535098/
https://ncbi.nlm.nih.gov/pubmed/23139020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9425-7
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