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Determination of the Dominant Arachidonic Acid Cytochrome P450 Monooxygenases in Rat Heart, Lung, Kidney, and Liver: Protein Expression and Metabolite Kinetics

Cytochrome P450 (P450)-derived arachidonic acid (AA) metabolites serve pivotal physiological roles. Therefore, it is important to determine the dominant P450 AA monooxygenases in different organs. We investigated the P450 AA monooxygenases protein expression as well as regioselectivity, immunoinhibi...

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Detalhes bibliográficos
Main Authors: El-Sherbeni, Ahmed A., Aboutabl, Mona E., Zordoky, Beshay N. M., Anwar-Mohamed, Anwar, El-Kadi, Ayman O. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535098/
https://ncbi.nlm.nih.gov/pubmed/23139020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9425-7
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