FGF regulates TGFβ signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression

Maintenance of normal endothelial function is critical to various aspects of blood vessel function but its regulation is poorly understood. In this study we show that disruption of baseline FGF signaling to the endothelium leads to a dramatic reduction in let-7 miRNA levels that in turns increases e...

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Detalhes bibliográficos
Main Authors: Chen, Pei-Yu, Qin, Lingfeng, Barnes, Carmen, Charisse, Klaus, Yi, Tai, Zhang, Xinbo, Ali, Rahmat, Medina, Pedro P., Yu, Jun, Slack, Frank J., Anderson, Daniel G., Kotelianski, Victor, Wang, Fen, Tellides, George, Simons, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534912/
https://ncbi.nlm.nih.gov/pubmed/23200853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.10.021
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