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FGF regulates TGFβ signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression

Maintenance of normal endothelial function is critical to various aspects of blood vessel function but its regulation is poorly understood. In this study we show that disruption of baseline FGF signaling to the endothelium leads to a dramatic reduction in let-7 miRNA levels that in turns increases e...

詳細記述

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書誌詳細
主要な著者: Chen, Pei-Yu, Qin, Lingfeng, Barnes, Carmen, Charisse, Klaus, Yi, Tai, Zhang, Xinbo, Ali, Rahmat, Medina, Pedro P., Yu, Jun, Slack, Frank J., Anderson, Daniel G., Kotelianski, Victor, Wang, Fen, Tellides, George, Simons, Michael
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534912/
https://ncbi.nlm.nih.gov/pubmed/23200853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.10.021
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