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FGF regulates TGFβ signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression
Maintenance of normal endothelial function is critical to various aspects of blood vessel function but its regulation is poorly understood. In this study we show that disruption of baseline FGF signaling to the endothelium leads to a dramatic reduction in let-7 miRNA levels that in turns increases e...
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| 主要な著者: | , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534912/ https://ncbi.nlm.nih.gov/pubmed/23200853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.10.021 |
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