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Basic principles of tumor-associated regulatory T cell biology

Due to the critical role of Foxp3(+) regulatory T cells (Tregs) in the regulation of immunity and the enrichment of Tregs within many human tumors, a number of emerging therapeutic strategies for the treatment of cancer involve the depletion or modulation of Tregs, with the aim of eliciting enhanced...

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Bibliografiske detaljer
Main Authors: Savage, Peter A., Malchow, Sven, Leventhal, Daniel S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534814/
https://ncbi.nlm.nih.gov/pubmed/22999714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.08.005
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