The RRM Domain of Human Fused in Sarcoma Protein Reveals a Non-Canonical Nucleic Acid Binding Site

Fused in sarcoma (FUS) is involved in many processes of RNA metabolism. FUS and another RNA binding protein, TDP-43, are implicated in amyotrophic lateral sclerosis (ALS). It is significant to characterize the RNA recognition motif (RRM) of FUS as its nucleic acid binding properties are unclear. Mor...

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מידע ביבליוגרפי
Main Authors: Liu, Xuehui, Niu, Chunyan, Ren, Jintao, Zhang, Jiayu, Xie, Xiaodong, Zhu, Haining, Feng, Wei, Gong, Weimin
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534766/
https://ncbi.nlm.nih.gov/pubmed/23200923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.11.012
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