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Neutralization of TSLP Inhibits Airway Remodeling in a Murine Model of Allergic Asthma Induced by Chronic Exposure to House Dust Mite

Chronic allergic asthma is characterized by Th2-typed inflammation, and contributes to airway remodeling and the deterioration of lung function. However, the initiating factor that links airway inflammation to remodeling is unknown. Thymic stromal lymphopoietin (TSLP), an epithelium-derived cytokine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Zhuang-Gui, Zhang, Tian-Tuo, Li, Hong-Tao, Chen, Fen-Hua, Zou, Xiao-Ling, Ji, Jing-Zhi, Chen, Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534685/
https://ncbi.nlm.nih.gov/pubmed/23300949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051268
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