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Inhibition of PI3K/Akt Pathway Impairs G2/M Transition of Cell Cycle in Late Developing Progenitors of the Avian Embryo Retina

PI3K/Akt is an important pathway implicated in the proliferation and survival of cells in the CNS. Here we investigated the participation of the PI3K/Akt signal pathway in cell cycle of developing retinal progenitors. Immunofluorescence assays performed in cultures of chick embryo retinal cells and...

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Detalhes bibliográficos
Main Authors: Ornelas, Isis Moraes, Silva, Thayane Martins, Fragel-Madeira, Lucianne, Ventura, Ana Lucia Marques
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534656/
https://ncbi.nlm.nih.gov/pubmed/23301080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053517
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