Platelet Activating Factor Blocks Interkinetic Nuclear Migration in Retinal Progenitors through an Arrest of the Cell Cycle at the S/G2 Transition

Nuclear migration is regulated by the LIS1 protein, which is the regulatory subunit of platelet activating factor (PAF) acetyl-hydrolase, an enzyme complex that inactivates the lipid mediator PAF. Among other functions, PAF modulates cell proliferation, but its effects upon mechanisms of the cell cy...

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Main Authors: Fragel-Madeira, Lucianne, Meletti, Tamara, Mariante, Rafael M., Monteiro, Robson Q., Einicker-Lamas, Marcelo, Bernardo, Robson R., Lopes, Angela H., Linden, Rafael
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029264/
https://ncbi.nlm.nih.gov/pubmed/21298035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016058
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