Model-based analysis of an adaptive evolution experiment with Escherichia coli in a pyruvate limited continuous culture with glycerol

Bacterial strains that were genetically blocked in important metabolic pathways and grown under selective conditions underwent a process of adaptive evolution: certain pathways may have been deregulated and therefore allowed for the circumvention of the given block. A block of endogenous pyruvate sy...

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Bibliographische Detailangaben
Hauptverfasser: Feuer, Ronny, Gottlieb, Katrin, Viertel, Gero, Klotz, Johannes, Schober, Steffen, Bossert, Martin, Sawodny, Oliver, Sprenger, Georg, Ederer, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534542/
https://ncbi.nlm.nih.gov/pubmed/23033959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1687-4153-2012-14
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