Drug–drug interaction through molecular structure similarity analysis

BACKGROUND: Drug–drug interactions (DDIs) are responsible for many serious adverse events; their detection is crucial for patient safety but is very challenging. Currently, the US Food and Drug Administration and pharmaceutical companies are showing great interest in the development of improved tool...

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Main Authors: Vilar, Santiago, Harpaz, Rave, Uriarte, Eugenio, Santana, Lourdes, Rabadan, Raul, Friedman, Carol
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 2012
Teme:
Research and Applications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534468/
https://ncbi.nlm.nih.gov/pubmed/22647690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2012-000935
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