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Microtubule S-glutathionylation as a potential approach for antimitotic agents

BACKGROUND: Microtubules have been one of the most effective targets for the development of anticancer agents. Cancer cells treated by these agents are characterized by cell arrest at G(2)/M phase. Microtubule-targeting drugs are, therefore, referred to as antimitotic agents. However, the clinical a...

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Библиографические подробности
Главные авторы: Chen, Wei, Seefeldt, Teresa, Young, Alan, Zhang, Xiaoying, Zhao, Yong, Ruffolo, John, Kaushik, Radhey S, Guan, Xiangming
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534152/
https://ncbi.nlm.nih.gov/pubmed/22703118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-245
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