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Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers

Controlling gene expression via small interfering RNA (siRNA) has opened the doors to a plethora of therapeutic possibilities, with many currently in the pipelines of drug development for various ocular diseases. Despite the potential of siRNA technologies, barriers to intracellular delivery signifi...

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Detalhes bibliográficos
Main Authors: Thakur, Ajit, Fitzpatrick, Scott, Zaman, Abeyat, Kugathasan, Kapilan, Muirhead, Ben, Hortelano, Gonzalo, Sheardown, Heather
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533807/
https://ncbi.nlm.nih.gov/pubmed/22686441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1754-1611-6-7
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