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Unusual C=C Bond Isomerization of an α,β-Unsaturated γ-Butyrolactone Catalysed by Flavoproteins from the Old Yellow Enzyme Family

An unexpected, redox-neutral C=C bond isomerization of a γ-butyrolactone bearing an exo-methylene unit to the thermodynamically more favoured endo isomer (k(cat) = 0.076 s(−1)) catalysed by flavoproteins from the Old Yellow Enzyme family was discovered. Theoretical calculations and kinetic data supp...

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Autors principals: Durchschein, Katharina, Wallner, Silvia, Macheroux, Peter, Zangger, Klaus, Fabian, Walter M F, Faber, Kurt
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533789/
https://ncbi.nlm.nih.gov/pubmed/23024004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201200475
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