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Murine tissue factor coagulant activity is critically dependent on the presence of an intact allosteric disulfide

Tissue factor activation (decryption) has been proposed to be dependent on the cysteine 186-cysteine 209 allosteric disulfide in the tissue factor extracellular domain. Tissue factor procoagulant activity is under the control of protein disulfide isomerase-dependent modulation and nitrosylation of t...

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Detalhes bibliográficos
Main Authors: van den Hengel, Lisa G., Osanto, Susanne, Reitsma, Pieter H., Versteeg, Henri H.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533678/
https://ncbi.nlm.nih.gov/pubmed/22801966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.069997
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