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Disassociation of insulin action and Akt/FOXO signaling in skeletal muscle of older Akt-deficient mice
The purpose of the present study was to determine the effect of Akt gene ablation on Akt/Forkhead Box O (FOXO) signaling and atrogene expression. This was accomplished by studying wild-type (WT) and isoform-specific Akt knockout (Akt1(−/−) and Akt2(−/−)) mice. The ability of insulin to promote Akt p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533617/ https://ncbi.nlm.nih.gov/pubmed/23100026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00358.2012 |
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